Message from the Chief
Mark Ratcliffe, M.D.
Professor and Vice-Chair, Department of Surgery,
UCSF
Chief of Surgery, San Francisco VA Medical Center
Make a Gift
A gift to the Department of Surgery helps us discover new treatments and cures.
Funding in Cardiothoracic Surgical Research
Parity for surgeon-scientists in research funding is critical for the development of new procedures and devices.
Robert Raffai, Ph.D.
Assistant Professor of Surgery
Contact Information
SFVAMC (112G)
4150 Clement Street
San Francisco, CA 9412
Phone: (415) 750-2115
Fax: (415) 750-2181
4150 Clement Street
San Francisco, CA 9412
Phone: (415) 750-2115
Fax: (415) 750-2181
Education
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1986-90, McGill University Faculty of Medicine, Canada, B.Sc., Biochemistry
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1990-93, University of Montreal, Canada, Other, Biochemistry
- 1993-98, University of Ottawa, Canada, Ph.D., Biochemistry
Fellowships
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1997-01, J. David Gladstone Institutes, Postdoctoral Fellow, Mouse Models of Human Disease
- 2001-04, J. David Gladstone Institutes, Postdoctoral Fellow, Mouse Models of Human Disease
Selected Publications
- Raffai RL, Dong LM, Farese RV, Weisgraber KH. Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E. Proc Natl Acad Sci U S A. 98: 11587-91, Sep/25/2001.
- Raffai RL, Weisgraber KH. Hypomorphic apolipoprotein E mice: a new model of conditional gene repair to examine apolipoprotein E-mediated metabolism. J Biol Chem. 277: 11064-8, Mar/29/2002.
- Raffaï RL, Hasty AH, Wang Y, Mettler SE, Sanan DA, Linton MF, Fazio S, Weisgraber KH. Hepatocyte-derived ApoE is more effective than non-hepatocyte-derived ApoE in remnant lipoprotein clearance. J Biol Chem. 278: 11670-5, Mar/28/2003.
- Raffai RL, Loeb SM, Weisgraber KH. Apolipoprotein E promotes the regression of atherosclerosis independently of lowering plasma cholesterol levels. Arterioscler Thromb Vasc Biol. 25: 436-41, Feb/2005.
- Zhang S, Picard MH, Vasile E, Zhu Y, Raffai RL, Weisgraber KH, Krieger M. Diet-induced occlusive coronary atherosclerosis, myocardial infarction, cardiac dysfunction, and premature death in scavenger receptor class B type I-deficient, hypomorphic apolipoprotein ER61 mice. Circulation. 111: 3457-64, Jun/28/2005.
